A small tumor is a large place

Throwing a “photoswitch” on cancer cells lights up the microenvironment and shows how tumor cells are guided toward a blood vessel

Bojana Gligorijevic
Albert Einstein College of Medicine
The Bronx

Small tumors are like minor surgery: If it’s your surgery, it’s not minor. If it’s your tumor, it’s not small. But increasingly, biologists are discovering that even a small tumor can be a large place and that a cell’s location⎯its microenvironment⎯within a tumor can decide its fate. That’s because cells are always signaling to each other, and figuring out what individual tumor cells are saying could tell researchers how to break up the cancer conversation.
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