Exploiting a cancer’s addiction

Researchers may have found a new way to slam the brakes on deadly ovarian cancer

Tulsiram Prathapam
University of California, Berkeley

Ovarian cancer cells are “addicted” to a family of proteins produced by a notorious oncogene, MYC, say cell biology researchers at the University of California, Berkeley. Blocking these oncoproteins shuts down cell proliferation in the deadliest cancer of the female reproductive system. On the basis of work in cultured human ovarian cancer cells, Tulsiram Prathapam, G. Steven Martin, and colleagues believe that their success with Myc protein inhibition could open a new therapeutic approach to a gynecological cancer that has lagged substantially behind treatment advances for other types.
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