The old joke is that biologists were the kids who good in science couldn't do the math. That's the old biology. Math and biology are melting together to form a new science of bioinformatics. The cause is data. Biology was being flooded by data. Bioinformatics has emerged to sort it out in new ways.
The work presented at the Monday "Ten AM Press Briefing" by Han-Yu Chuang from the Bioinformatics Program at the University of California, San Diego, demonstrated how data can be stood on its head, flipped over, and recombined with other data. Her audacious goal was to make predictions on whether or not a particular tumor sample was like to metastasize based on computational analysis of overlapping patterns of signaling pathways and protein complexes. It was "dry lab" biology on a large number-crunching scale. And it seems to offer an entirely new way to look at cancer as "a disease of pathways," says Chuang.
To read the whole story, go to:
https://www.ascb.org/ascbsec/press/embargo/ASCB-pressbook08_Ideker.pdf
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